The story of how one company triggered the worst drug epidemic in American history. Look into the epicenter of America's struggle with opioid addiction, from a distressed Virginia mining community, to the hallways of the DEA, and to the opulence of "one percenter" Big Pharma Manhattan.


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Michael Keaton
Samuel Finnix (8 episodes)

Peter Sarsgaard
Rick Mountcastle (8 episodes)

Michael Stuhlbarg
Richard Sackler (8 episodes)

Will Poulter
Billy Cutler (8 episodes)

John Hoogenakker
Randy Ramseyer (8 episodes)

Kaitlyn Dever
Betsy Mallum (8 episodes)

Rosario Dawson
Bridget Meyer (8 episodes)

Will Chase
Michael Friedman (8 episodes)

Cleopatra Coleman
Grace Pell (8 episodes)
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