As a U.S. Deputy Marshal, based on Miami, Florida's Gold Coast, Karen must deal with the underbelly of South Beach nightlife and Palm Beach high life while tracking down fugitives. She also struggles to win the respect of her fellow officers. Karen occasionally gets advice from her father, a retired Miami police officer turned private investigator, who is Karen’s confidant, counselor, and confessor.

Karen Sisco (2003)
01h 00m
Overview
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Top Billed Cast
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Carla Gugino
Karen Sisco (10 episodes)

Bill Duke
Amos Andrews (10 episodes)

Robert Forster
Marshall Sisco (10 episodes)

Carlos Ponce
Will (10 episodes)

Kate Walsh
(2 episodes)

Danny DeVito
Charlie Lucre (2 episodes)

Peter Horton
(1 episode)

Benito Martinez
(1 episode)

Moira Sinise
(1 episode)