Samantha Newly has been a bad, bad girl. But thanks to an 8-day coma, she can't remember a thing. Fortunately her best friend Andrea is by her side with a cocktail and the 4-1-1 on every dirty deed. But the more Sam pieces together her past, the less she likes her old self. Maybe this is a chance to start over and do it all again.
Samantha Who? (2007)
She's been a bad, bad girl... Good thing she can't remember.
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Christina Applegate
Samantha Newly (35 episodes)
Jennifer Esposito
Andrea Belladonna (35 episodes)
Kevin Dunn
Howard (35 episodes)
Melissa McCarthy
Dena (35 episodes)
Tim Russ
Frank (35 episodes)
Barry Watson
Todd (35 episodes)
Jean Smart
Regina Newly (35 episodes)
Rick Hoffman
Chase Chapman (9 episodes)
Stephen Rannazzisi
Seth (6 episodes)
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